Experience the groundbreaking capabilities of the NanoOne bio package, the only 2PP printer with an integrated incubation system. The NanoOne’s bio variant combines the potential for biocompatible applications with the characteristic high precision and versatility of the NanoOne 1000, achieving unparalleled precision in 3D printing of structures in the presence of living cells. From creating cell models that mimic natural tissue topography to the sterile fabrication of cell scaffolds, NanoOne bio opens doors to a new era in biomedical research. Join us in shaping the future of bioprinting.
Customized beyond precise bioprinting
NanoOne systems offer both a standard configuration and the flexibility to customize with additional modules to meet specific application demands. Easily explore upgrade options to ensure your NanoOne bio package meets your requirements. These upgrades can be retrofitted at any time, ensuring your system evolves alongside your innovative manufacturing approaches. NanoOne Bio’s capabilities extend beyond bioprinting, making it versatile for various applications.
Design with a focus on biological applications
Specifications of the system
|
System type |
Desktop multiphoton laser lithography system |
|---|---|
|
Printing process |
Layer-by-layer 2-photon polymerization |
|
Light source |
Femtosecond fiber laser |
|
Laser wavelength |
780 nm |
|
Laser power |
1000 mW |
|
Scanner |
Galvanometer scanner |
|
Stage |
Long-range piezo stage |
|
Maximum travel range |
Up to 120 x 100 x 49 mm |
|
Stage address grid |
10 nm |
|
System dimensions |
Benchtop system 94.0 x 71.0 x 65.0 cm³ |
|
Total weight |
156 kg |
Overview of NanoOne models
| |  |  | |  |
|---|---|---|---|---|
|
Average Power |
250 mW |
1,000 mW |
1,000 mW |
400 mW |
|
Laser wavelength |
780 nm |
780 nm |
780 nm |
515 nm |
|
Pulse length |
90 fs |
90 fs |
90 fs |
90 fs |
|
Standard objectives |
40x NA 1.4 20x NA 0.7 10x NA 0.4 |
40x NA 1.4 20x NA 0.7 10x NA 0.4 5x NA 0.25 |
40x NA 1.4 20x NA 0.7 10x NA 0.4 10x NA 0.3 5x NA 0.25 |
40x NA 1.4 20x NA 0.7 10x NA 0.4 |
|
System dimensions Total weight |
58.5 x 71.0 x 65.0 cm³ 124 kg |
58.5 x 71.0 x 65.0 cm³ 124 kg |
94.0 x 71.0 x 65.0 cm³ 156 kg |
58.5 x 71.0 x 65.0 cm³ 124 kg |
|
System type |
Desktop multiphoton laser lithography system |
|---|---|
|
Printing process |
Layer-by-layer 2-photon polymerization |
|
Light source |
Femtosecond fiber laser |
|
Scanner |
Galvanometer scanner |
|
Stage |
Long-range piezo stage |
|
Maximum travel range |
Up to 120 x 100 x 49 mm |
|
Stage address grid |
10 nm |
The only true incubation system for 2PP-3D printing systems
The UpNano BioUnit is the centerpiece of the NanoOne’s bio variant and an upgrade opportunity for all printing systems. It’s the only true incubation system for high-resolution 3D printing, providing a native, stress-free environment for the living cells during the printing process. The stage-top incubation system offers a plethora of features, allowing adjustments to match the preferred environmental conditions of the respective cell type and ensures these conditions during printing.
High-resolution bioprinting with living cells
Our comprehensive incubation system comprises of two controller units, a heating panel, and a CO2 gas incubation system. The gas incubation system provides a regulated gas atmosphere along with precise humidity levels within a continuous gas stream circulated through the incubation chamber. Meanwhile the heating panel maintains the ambient temperature required by the specific cell type, ensuring a native environment during the printing process and thus preserving cell viability.
Experience the future of bioprinting with NanoOne
Direct printing of living cells for cutting-edge research, unrestricted substrate options, and precise control of environmental conditions for optimal cell viability.
Revolutionize the manufacturing of 3D scaffold structures
Biocompatible resins, perfect for mimicking cellular microenvironments and setting new standards in preclinical research and therapeutic strategies.
Rethinking production of microfluidic and microphysiological systems
UpNano’s dip-in free proprietary process unlocks new possibilities in 3D printing directly within a microfluidic chip or cell culture well.
Examples of compatible cell-culture substrates
Biocompatible 3D printing resins according to EN ISO 10993-5
In addition to a cell-compatible process, the choice of printing resin is crucial. With our collaboration with the Belgian company BIO INX®, we have developed a biofunctional material portfolio that is not only cell-compatible but also optimized for the NanoOne platform. Moreover, UpNano offers a portfolio of five biocompatible resins certified as non-cytotoxic according to EN ISO 10993-5:2009. Each of these resins, in addition to being biocompatible, has unique properties that highlight the wide range of possible applications. Choose UpNano for both cell compatibility and versatility in resin selection.
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